Diane 35 is a combined drug, containing estrogen – ethinyl estradiol and antiandrogen – cyproterone acetate, possessing gestagen properties. Diane 35 maintains high viscosity of cervical mucus, making it difficult the sperm penetration into the uterus and contributes to ensure the contraceptive effect. Cyproterone acetate blocks androgen receptors and reduces the androgenization phenomena in women (increase in sebum release, hair growth in male pattern, hair loss on the head).
Manifestations of acne are reduced and the appearance of new acne is prevented in the case of Diane 35 use. Along with antiandrogen properties, cyproterone acetate possesses gestagen activity that leads to the ovulation inhibition and contraceptive effect, respectively. Contraceptive action of Diane 35 manifests to 14 day from the start of administration and is maintained during 7-day pause.
Diane 35 dosage form
Diane-35 is supplied in a calendar packaging of 21 pills.
Indication for Diane 35 use
Prevention of pregnancy in women with androgenization phenomena (appearance of male traits in women, caused by male sex hormones). Androgenization phenomena include: acne, blackheads, seborrhea, mild forms of androgenetic alopecia, baldness in women under the action of male sex hormones, hirsutism, excessive hairiness in women in male pattern.
Method of application:
To prevent pregnancy during the first cycle of treatment, Diane 35 is taken of 1 tablet from 5th to 25th day of menstrual cycle, the 1st day of cycle is considered to be the 1st day of menstruation. Then, after 5-day break during which menses occur, the next Diane 35 packaging (21 tablets) should be started to use.
Risk of cardiovascular complications increases when smoking (especially after 35 years). Before to use Diane 35 birth control, as well as in its regular administration, gynecologist’s consultations are needed.
Diane 35 use should be immediately terminated in case of the following symptoms: early signs of phlebitis (inflammation of the vein wall), thrombosis (blockage of vessels by clot of blood), embolism (blood vessels obstruction) – veins swelling, unusual pain in the legs, chest pain when breathing or coughing, feeling of compression in the chest, first appeared migraine-like headaches, sudden problems with hearing and vision, motor disorders. Risk of thrombosis increases in case of high blood pressure.
Diane 35 medication is canceled in hepatitis, jaundice, itch, cholestasis (bile stagnation in the bile ducts), acceleration of epileptic seizures, primary or secondary occurrence of porphyria (disease, associated with metabolism disorder of porphyrins / pigment).
Vomiting or diarrhea can lead to the excretion of Diane 35 pill from the body, so when these symptoms take place during the day, Diane 35 pill should be taken repeatedly. In longer preservation of these symptoms, it is necessary temporarily to use other methods to prevent pregnancy.
Diane 35 side effects
Diane 35 side effects may include chest pain, stomach pain, nausea, headaches, changes in weight and sex drive, depressive states, chloasma (yellowish-brown spots on the skin, intermediate bleeding.
More serious Diane 35 side effects may include severe headaches (migraine), acute visual impairment, the first signs of thrombophlebitis (inflammation of the veins wall with their blockage) or thromboembolic phenomena (blood vessels obstruction), jaundice, severe high blood pressure.
Stop taking Diane 35 medication and call your doctor if you have these side effects.
Contraindications for Diane 35 use
Diane 35 is contraindicated in pregnancy, breastfeeding, liver disease, idiopathic jaundice or severe skin itching during pregnancy in anemneze, Dubin-Johnson syndrome (a hereditary liver disease, accompanied by jaundice) and Rotor (an inherited liver disease, characterized by a moderate increase in the content of conjugated bilirubin in the blood). Diane 35 is also contraindicated in breast cancer or endometrial (inner layer of the uterus) – even after the treatment, lipid metabolism disorder, bullous dermatosis (skin disease) during pregnancy in the history, otosclerosis (progressive hearing loss and tinnitus) with deterioration during previous pregnancies.
Pregnancy:
Do not take Diane 35 during pregnancy and breastfeeding.
Diane 35 drug interactions
Some medications can reduce Diane 35 effectiveness, which may result in pregnancy. Before to use Diane 35, you should tell your doctor about all medicines you are taking. This includes prescription, over-the-counter, vitamin and herbal means. Do not take a new medication without telling your doctor.
Diane 35 overdose
Serious side effects were not revealed in overdose.
Diane 35 overdose symptoms are vomiting, slight vaginal bleeding (in young girls). Overdose treatment is symptomatic. There is no specific antidote.
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Before to buy Diane 35 contraceptive pills you should consult your doctor.